Pyruvate Oxidase

Pox; Phosphate-dependent pyruvate oxidase

Pyruvate Oxidase is an important oxidoreductase that oxidizes pyruvate for energy and hydrogen peroxide production, and plays a key role in bacterial metabolism. Pyruvate Oxidase enhances bacterial respiration by increasing ATP production, thereby increasing the bacterial growth rate and vitality. Pyruvate Oxidase produces hydrogen peroxide, inhibits the growth of other bacteria, thereby providing a competitive advantage for pyruvate oxidase producing bacteria. Pyruvate Oxidase also regulates cellular redox signaling pathway, regulates the physiological functions of cells. Pyruvate Oxidase dysfunction leads to bacterial infection, microbial community imbalance, and metabolic disorders^[1].

References:

[1]. Cornacchione LP, et al., Hydrogen peroxide-producing pyruvate oxidase from Lactobacillus delbrueckii is catalytically activated by phosphotidylethanolamine. BMC Microbiol. 2020 May 24;20(1):128. [Content Brief]

Pyruvate Oxidase Related Products (1):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-P2891

Pyruvate Oxidase, Microorganisms
Pyruvate Oxidase, Microorganisms (PoxB) is a thiamine pyrophosphate-dependent oxidase that catalyzes the oxidative decarboxylation of pyruvate to acetyl phosphate, carbon dioxide and water. Pyruvate oxidase is an important enzyme in bacterial metabolism and is often used in biochemical research.

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